HIV-1integrase相关论文
The α-helix Stabilization of the HIV-1 Integrase Sequence Based Peptide Inhibitor by the Introductio
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Study on action mechanism of a dual-effect inhibitor against both wild-type and drug-resistant mutan
Background: HIV-1 integrase (IN), which responsible for strand transfer (ST) reaction by inserting the viral DNA into ho......
The rapid emergence of cross-resistance to the integrase strand transfer inhibitors (INSTIs) has become a serious proble......
Hiv-1 整合酶是抗艾滋病药物的重要作用靶点,芳基二酮酸类化合物被认为是最有效的Hiv-1 整合酶抑制剂 [1,2]。在前期发现1,2,3-三......
The target compound Ⅳ (C20H21N) was synthesized through four-step reactions and structurally determined by single-cryst......
Computational Investigation of the Anti-HIV Activity of Chinese Medicinal Formula Three-Huang Powder
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目的:研究治疗获得性免疫缺陷综合症药物raltegravir的合成工艺.方法:经过成氨基腈,苄氧羰基保护氨基,从腈成氨肟,环合成二羟基嘧......
目的研究蚬壳花椒茎木中的活性成分,方法应用硅胶柱色谱分离和纯化,用IR、MS和NMR等谱学方法解析化合物结构,并用MIA法测试化合物......
